报告人：Huixiao Hong, senior scientist at Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration.

主持人🧑🏻‍🎤：石铁流  教  授  

时  间👩🏼‍⚖️：11月10日13:30

地  点🤚🏻：闵行校区生科院534报告厅

主办单位:天美娱乐 科技处

 

报告人简介： 

Dr. Huixiao Hong current is a senior scientist at Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration. He obtained his PhD in Computational Chemistry from Nanjing University in 1990. He moves into Bioinformatics field after many years’ experiences in structure chemistry and chemoinformatics field. He has participated into FDA leading MAQC and SEQC project during past several years and has published over 130 papers. 

 

报告内容简介👨🏻：

Realizing personalized medicine requires integrating diverse data types with bioinformatics. The most vital data are genomic information for individuals that are from advanced next-generation sequencing (NGS) technologies at present. The technologies continue to advance in terms of both decreasing cost and sequencing speed with concomitant increase in the amount and complexity of the data. The prodigious data together with the requisite computational pipelines for data analysis and interpretation are stressors to IT infrastructure and the scientists conducting the work alike. Bioinformatics is increasingly becoming the rate-limiting step with numerous challenges to be overcome for translating NGS data for personalized medicine. I will discuss some key bioinformatics tasks, issues, and challenges in contexts of IT requirements, data quality, analysis tools and pipelines, and validation of biomarkers.