报告题目：Exploring the mechanisms of plant infection by the grey mould fungus Botrytis cinerea

报告人🎻：德国 凯德斯劳滕大学植物病理学Matthias Hahn教授

主持人：许  玲  教授

开始时间♚：9月9日 下午1:30 -3:00

讲座地址：闵行生科院159教室

主办单位：天美娱乐、科技处

 

报告人简介🛍️：Matthias Hahn教授于1986年获瑞士苏黎世Federal Institute of Technology（ETH）博士学位，现任德国Kaiserslautern University植物病理学教授。Matthias Hahn教授的主要研究方向为植物病原真菌的致病机理与病害控制🙅🏿‍♀️，近年来他在重要植物病害灰霉菌（Botrytis cinerea）的孢子萌发阶段信号转导及该菌的多重耐药性机理方面取得了重要研究进展🤾，主要成果发表在Molecular Plant Pathology👦🏿，Molecular Microbiology，PLoS Pathogen，Phytopathology等植物病理学领域重要刊物上🫶🏽🫷🏻。Hahn教授讲座拟以“探索灰霉菌侵染植物分子机理的新进展”为主题报告➗，还将以系列专题讲座的形式📑，介绍比较基因组学、信号转导网络💇🏼、活细胞成像🥫、基因敲除新技术等前沿的研究技术在植物病理学中的应用。

 

报告摘要：Botrytis cinerea is a ubiquitous plant pathogen that attacks hundreds of different plant species. Our recent work has shown that populations of B. cinerea are genetically heterogeneous, consisting of several genotypes that express different degrees of host adaptation. We have investigated the role of BMP1 MAP kinase cascade and the plasma membrane sensor proteins, Msb2 and Sho1, during different stages of host infection. Mutants in the corresponding genes show defects in germination, appressorium formation and induction of necrotic lesions. While some of these defects are comparable to those in similar mutants of other plant pathogenic fungi, others are unique to B. cinerea. Msb2 acts as a surface sensor that triggers appressorium formation, and is required for normal phosphorylation of BMP1 in germlings. Mutants lacking Sho1 have a minor defect in surface sensing, and are able to form initial lesions at the inoculation sites, but the lesions fail to expand. This phenotype was correlated with the inability of the mutant to acidify the growth medium in vitro and the plant tissue during infection. By using a comparative genomic approach, we have observed differences in the ability of B. cinerea strains and related Botrytis species to synthesis secondary metabolites. Mutants were generated to analyse the role of toxins in plant infection.