报告题目📖🐦‍⬛：Molecular Determinants of the Stem Cell State in the Mammalian Male Germline

报告人🚔：Jon M. Oatley, Associate Professor, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University.

主持人：王媛 教授

报告时间👩‍🔧：2017年6月26日 10:00-11:30

报告地点💆🏽‍♀️：闵行生科院534报告厅

主办单位：天美娱乐，科技处

 

报告人简介：

1994-1999  University of Nevada-Reno, B.S. in Animal Sciences

2001-2004  Washington State University, Ph.D. in Animal Sciences/Reproductive Biology, Mentor: Dr. Jerry J. Reeves

2011-2014  Assistant Professor, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University

2014-Present  Associate Professor, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University.

2013-Present  Director, Center for Reproductive Biology, Washington State University

 

报告摘要：

Dr. Oatley will discuss the key functional and molecular features are that define a stem cell in the mouse male germline, in particular our discovery of ID4 as a specific marker of spermatogonial stem cells, the generation of an Id4-eGfp transgenic reporter line, and the role that ID4 plays in maintaining the stem cell state. He will talk about how we have utilized the Id4-eGfp transgenic to develop a high throughput screen for identifying novel transcription factors that are important for maintenance of the stem cell pool.